Please use this identifier to cite or link to this item: 192.168.6.56/handle/123456789/74752
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dc.contributor.authorRams-Baron, Marzena-
dc.contributor.authorJachowicz, Renata-
dc.contributor.authorBoldyreva, Elena-
dc.contributor.authorZhou, Deliang-
dc.contributor.authorJamroz, Witold-
dc.contributor.authorPaluch, Marian-
dc.date.accessioned2019-07-02T06:13:38Z-
dc.date.available2019-07-02T06:13:38Z-
dc.date.issued2016-
dc.identifier.isbn978-3-319-72002-9-
dc.identifier.urihttp://10.6.20.12:80/handle/123456789/74752-
dc.descriptionLow aqueous solubility of active pharmaceutical ingredients (APIs) is one of the most important challenges facing drug development researchers today. With the development of computational chemistry and high throughput screening methods it is possible to obtain a large number of compounds with attractive therapeutic activity. However, at the same time the selection of novel active molecules with suitable biopharmaceutical properties (like solubility, intestinal permeability) becomes a great challenge and a bottleneck in drug development.Statistically, more than 40% of approved drugs and even 70–90% of those under investigations are poorly water-soluble and additional efforts are required to improve their water solubility.en
dc.languageenen
dc.language.isoenen_US
dc.publisherSpringer International Publishing AGen_US
dc.subjectDrugen_US
dc.titleAmorphous Drugsen_US
dc.typeBooken_US
Appears in Collections:Chemistry

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